However, this lipase exhibits a broader substrate specificity than simply platelet activating factor.
2.
Two other pro-inflammatory mediators causing oxidative stress that are inhibited by Troxipide include the Platelet Activating Factor ( PAF ).
3.
BAFF shares many activities with PAF ( Platelet Activating Factor ) and they are both markers of non-IgE-mediated reactions in food-reactivity.
4.
Icos hopes to begin clinical trials this year of PAF-AH, an enzyme that shuts off platelet activating factor, a cause of inflammation.
5.
In addition mild hypothermia may reduce the activation of the cytokine and coagulation cascades through increased activation of suppressor signalling pathways, and by inhibiting release of platelet activating factor.
6.
Human ABC transporters are involved in several diseases that arise from cone rod dystrophy, and others . possibly related to the outward transport of the lipid platelet activating factor ( PAF ).
7.
Moreover, molecules such as the platelet activating factor ( PAF ) and prostaglandins, which are produced upon microglia / macrophages and astrocytes functional interactions, have been reported to mediate cell damage in primary neural cell cultures and neural cell lines with immature phenotype.
8.
This suggests that chemical factors that are released from microglial cells are contributing to neuronal loss . " It has become more and more apparent that HIV-1 infected microglial cells actively secrete both endogenous neurotoxins such as TNF-?, IL-1?, CXCL8 / IL-8, glutamate, quinolinic acid, platelet activating factor, eicosanoids, and NO as well as the neurotoxic viral proteins Tat, gp120, and gp41 ."
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